EPI-peptide designer: a tool for designing peptide ligand libraries based on epitope–paratope interactions
نویسندگان
چکیده
منابع مشابه
Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors.
G protein-coupled receptors (GPCRs) are considered to represent the most promising drug targets; it has been repeatedly said that a large fraction of the currently marketed drugs elicit their actions by binding to GPCRs (with cited numbers varying from 30-50%). Closer scrutiny, however, shows that only a modest fraction of (≈60) GPCRs are, in fact, exploited as drug targets, only ≈20 of which a...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2016
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btw014